Can I take creatine while on GLP-1 medications like semaglutide?

Yes, it is often recommended. Since GLP-1 medications can lead to a reduction in muscle mass along with fat loss, creatine helps maintain the muscle tissue you have. It works by supporting cellular energy and hydration, which can be helpful if your appetite and nutrient intake have decreased.

About Creatine Monohydrate Benefits: A Professional Guide for Muscle and Health

This answer is drawn from the full physician-reviewed guide to Creatine Monohydrate Benefits: A Professional Guide for Muscle and Health on the GOAL.MD Vitamin Shop learning hub. Read the full guide for mechanism of action, evidence, dosing, safety, and interactions.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.