Do I need to keep this supplement in the refrigerator?

While many professional-grade probiotics are shelf-stable for a period, we generally recommend refrigeration after opening to ensure maximum potency and longevity of the live cultures, especially in warmer climates.

About Probiotic Synergy Guide: Benefits for Digestion and Gut Health

This answer is drawn from the full physician-reviewed guide to Probiotic Synergy Guide: Benefits for Digestion and Gut Health on the GOAL.MD Vitamin Shop learning hub. Read the full guide for mechanism of action, evidence, dosing, safety, and interactions.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.