Does semaglutide cause hair loss?

Semaglutide itself is not a direct cause of hair loss, but rapid weight loss of any kind can trigger a temporary shedding called telogen effluvium. This is usually reversible and often improves once weight stabilizes and nutrition — especially protein, iron, and overall calories — is adequate. If shedding is significant or persistent, talk to your physician.

Why it can happen

Telogen effluvium is a stress response in which more hair follicles than usual enter the shedding phase. Significant or rapid weight loss, low protein intake, and nutrient gaps are common triggers — it's linked to the weight loss itself more than to the medication.

How to reduce the risk

Aim for steady rather than extreme weight loss, keep protein intake adequate, and ensure enough iron, zinc, and overall calories. Shedding is typically temporary and resolves within several months. A physician can check for other contributing causes if it persists.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.