What are the side effects of NAD+ therapy?

The effects most commonly reported with NAD+ are related to how quickly it is administered: flushing, warmth, nausea, chest or stomach tightness, lightheadedness and fatigue, most often described with rapid IV infusion. Reported effects are usually short-lived, but long-term safety data are limited and your health history and medications should be reviewed by a physician first.

Common, usually mild effects

Rapid delivery, particularly IV, is the effect most often described: nausea, flushing, a tight sensation in the chest, cramping and lightheadedness. How any preparation is administered is a clinical decision made by your physician, not something to adjust on your own.

Who should be cautious

People who are pregnant or breastfeeding, or who have significant heart, liver, or kidney conditions, should only use NAD+ under physician guidance. Tell your physician about all medications and supplements you take so your plan is individualized and safe.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.