What happens if you miss a dose of semaglutide?

If you miss a weekly dose of semaglutide, general guidance for once-weekly injectable semaglutide is to take it as soon as you remember if it's within about 5 days (48 hours for some products), then resume your regular schedule. If more time has passed, skip the missed dose and take the next one as scheduled — never double up. Always follow your physician's and product's specific instructions.

General rule of thumb

For once-weekly injectable semaglutide, if the missed dose is caught within the window your product specifies (often up to about 5 days), take it right away. If it's been longer, skip it and continue with your next scheduled dose. Do not take two doses close together to 'catch up.'

If you miss several weeks

Missing multiple weeks can mean you need to restart at a lower dose to avoid side effects, because tolerance can fade. Contact your physician before resuming after a long gap so they can advise on the safest way to continue.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.