What is NAD+ and what does it do?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell that is essential for energy production, DNA repair, and cellular function. Levels naturally decline with age. NAD+ therapy — via injection or IV — aims to restore these levels to support energy, cognition, metabolism, and healthy aging. It is used under physician supervision.

Why NAD+ matters

NAD+ powers the mitochondria (your cells' energy factories) and activates repair enzymes involved in DNA maintenance and cellular stress response. As NAD+ declines with age, cells become less efficient — which is why restoring it is a focus of longevity medicine.

How it's used

Physician-supervised NAD+ is delivered by injection or IV and is often used to support energy, mental clarity, and recovery. Dosing is individualized and titrated for tolerability. Discuss your health history with a physician to determine if it's appropriate for you.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.