Why do I have sulfur burps on tirzepatide?

Sulfur or 'rotten egg' burps on tirzepatide happen because the medication slows digestion, letting food sit longer and produce sulfur-containing gas. They are usually harmless and often improve over time or with dietary changes. Smaller meals, less high-fat and high-sulfur food, and staying hydrated typically help.

Why it happens

Slower gastric emptying means food ferments longer in the stomach, producing hydrogen sulfide gas that causes the smell. It is a mechanical effect of how the medication works, not usually a sign of a serious problem.

What helps

Eat smaller, lower-fat meals; reduce high-sulfur foods (eggs, red meat, some cruciferous vegetables) if they trigger it; stay hydrated; and avoid lying down right after eating. Tell your physician if it comes with severe pain or persistent vomiting.

Medically reviewed by Dr. Michael Mimlitz, MD (NPI 1508891870), Chief Physician of GOAL.MD. Physician-supervised telehealth. More at goal.md/answers.