Hypnos: sleep-theme components and what is actually known

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Hypnos is a named combination of DSIP, selank, CJC-1295, and ipamorelin. It pairs a peptide named for sleep research with an anxiety-context neuropeptide and two growth hormone releasing approaches. No study of the combination was identified.

Composition

  • dsip
  • selank
  • cjc-1295
  • ipamorelin

Overview

Sleep is the goal people most often bring to this category, and it is also the goal with the strongest established alternatives. Cognitive behavioural therapy for insomnia has substantial trial evidence. Nothing in this grouping does. The page states both facts, because a reader deciding what to do deserves the comparison rather than only the product description.

Why these are grouped

The rationale offered is that a sleep-associated peptide, an anxiety-context peptide, and growth hormone release, which naturally peaks during deep sleep, might reinforce one another. That is a story built from adjacent observations. No published work tested it.

What each ingredient contributes

dsip

Delta sleep-inducing peptide, named for early research in sleep physiology. Human evidence is old, limited, and inconsistent.

selank

A Russian-approved neuropeptide studied in anxiety contexts. Not FDA-approved.

cjc-1295

A growth hormone releasing hormone analogue included on the reasoning that growth hormone release relates to deep sleep.

ipamorelin

A secretagogue acting at a different receptor, included for pathway breadth.

Combination evidence

  • No published or registered study of the Hypnos combination was identified.
  • No sleep architecture data exist for this grouping.
  • No safety data describe the four used together.

DSIP's name reflects early research interest rather than demonstrated efficacy, and subsequent work did not establish it as a sleep therapy. Selank has Russian research and no FDA review. The growth hormone components have limited human data. Nothing describes the combination.

Preclinical rationale

  • DSIP was isolated in early sleep physiology research and studied for effects on sleep architecture.
  • Growth hormone release peaks during slow wave sleep, which is the association behind including secretagogues.
  • Anxiety and sleep quality interact, which is the rationale for the selank component.

What is not established

  • Any effect of the combination on sleep onset, duration, or architecture.
  • Whether DSIP produces a measurable human sleep effect at all.
  • Safety of the combination at any duration.
  • Interaction with sedatives and sleep medicines.

Questions to discuss with a physician

  • Should I be screened for sleep apnoea before anything else?
  • What does cognitive behavioural therapy for insomnia involve, and would it fit my situation?
  • Is there any evidence for this grouping in sleep?
  • How would this interact with what I take now?
  • How would we measure sleep objectively?

This page is educational. Nothing here can be ordered, and nothing here is a prescription or medical advice. Compounded preparations are not FDA-approved. To ask about current availability, visit goal.md/peptides/connect or call or text 314-907-3103.

Medically reviewed by Michael Fitch, MD, MD. Last reviewed 2026-08-15.