Samson & Delilah: composition and what the name does not mean

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Samson & Delilah is a named combination of GHK-Cu, CJC-1295, ipamorelin, and TB-500. It mixes copper peptide and tissue repair research with two growth hormone releasing approaches. No study of the combination was identified.

Composition

  • ghk-cu
  • cjc-1295
  • ipamorelin
  • tb-500

Overview

This grouping sits between the growth hormone axis stacks and the longevity ones. Two components stimulate growth hormone release, and two come from tissue and skin signalling research. The page keeps those as two separate evidence discussions because that is what they are, and it is explicit that the biblical name carries no information about effect.

Why these are grouped

The rationale offered is that skin and connective tissue signalling might be discussed alongside growth hormone axis activity for people focused on tissue quality. That is a theme, not a result. No published work evaluated the four together.

What each ingredient contributes

ghk-cu

A copper-binding peptide with published skin and wound research, largely topical.

cjc-1295

A growth hormone releasing hormone analogue with limited human pharmacology data.

ipamorelin

A secretagogue acting through a different receptor, included for pathway breadth.

tb-500

A synthetic fragment related to thymosin beta-4, studied in animal repair models with no adequate human trial base.

Combination evidence

  • No published or registered study of this combination was identified.
  • No human safety data exist for these four substances together.
  • No evidence supports claims about hair, skin appearance, strength, or sexual function for this grouping.

GHK-Cu has the most credible published work here and it is largely topical. The growth hormone components have limited human data. TB-500 is preclinical. None of that describes the combination.

Preclinical rationale

  • Copper peptides appear in skin remodelling and wound healing research.
  • Thymosin beta-4 related fragments appear in animal models of tissue repair.
  • Two receptor pathways converge on pituitary growth hormone release.

What is not established

  • Any effect on hair growth or appearance.
  • Any effect on strength or physical performance.
  • Whether topical skin findings translate to systemic administration.
  • Safety of the combination at any duration.

Questions to discuss with a physician

  • Is there evidence for any of this applied to my actual goal?
  • What would established care do for skin, hair, or tissue concerns?
  • How does the growth hormone part interact with my glucose handling?
  • What would you monitor?
  • What should I not expect?

This page is educational. Nothing here can be ordered, and nothing here is a prescription or medical advice. Compounded preparations are not FDA-approved. To ask about current availability, visit goal.md/peptides/connect or call or text 314-907-3103.

Medically reviewed by Michael Fitch, MD, MD. Last reviewed 2026-08-15.