You’re finally ready to grow your family — but you’ve also made huge strides in your weight loss journey with GLP-1 medications like semaglutide or tirzepatide.
So now you’re asking the tough question:

Can I stay on GLP-1s while trying to conceive?
Or even more urgent:

Will stopping them derail my progress or affect my chances of a healthy pregnancy?

You’re not alone in asking — and you deserve clear answers.
Here’s what the science says, what doctors recommend, and how GOAL.MD helps you navigate this life stage with confidence.

💡 Want expert support on how to transition your GLP-1 plan for pregnancy? Start with a free provider consult here

What Do the Guidelines Say About GLP-1s and Fertility?

The Short Answer:

No — GLP-1s like semaglutide and tirzepatide are not recommended while actively trying to conceive or during pregnancy.

Why?
Because there simply isn’t enough safety data yet on how these medications affect fetal development. While animal studies have shown potential risks, there haven’t been enough human studies to make it safe.

That doesn’t mean you’ve done anything wrong by using them before trying.
It just means you’ll need a thoughtful plan for transitioning off — and GOAL.MD can help with that.

Why GLP-1s Are Paused for Conception and Pregnancy

GLP-1 medications work by mimicking natural hormones that regulate appetite, insulin response, and digestion.
But they also cross the placenta in animal studies, and some trials showed fetal harm when dosed during gestation.

According to prescribing guidelines:

• Semaglutide (Ozempic®, Wegovy®): Patients are advised to stop the medication at least 2 months before conceiving

• Tirzepatide (Mounjaro®): Recommend stopping at least 1 month prior to conception

📌 These windows are based on each drug’s half-life — how long it stays in your system.

Can You Use GLP-1s to Reach a Healthy Weight Before Pregnancy?

Absolutely — and for many patients, that’s the point.

Being at a healthier weight before pregnancy can:

• Lower your risk of gestational diabetes

• Improve ovulation and menstrual regularity (especially in PCOS)

• Reduce complications during delivery

• Support healthier outcomes for baby

✅ Many OB/GYNs now recommend short-term GLP-1 use as a preconception strategy, as long as the medication is paused at the right time.

We’ve supported countless women who used compounded semaglutide to get to a stable weight — and then safely paused before trying.
We can help you do the same.

But Will I Gain Weight After Stopping?

This is one of the biggest concerns we hear.

And here’s the truth:
Some rebound weight gain is possible, especially if:

• You stop cold turkey

• You haven’t built sustainable habits

• Your hormones or insulin resistance were driving hunger before

But with the right plan, you can maintain your progress — even without the shot.

Our maintenance protocol includes:

• Nutrition coaching (yes, you still get Betsy!)

• Gentle activity tracking

• Optional non-GLP-1 appetite support (when medically safe)

FAQ Section

Q: What happens if I accidentally get pregnant while on a GLP-1?
A: Contact your OB right away. In most cases, they will recommend stopping the medication immediately. Don’t panic — early exposure doesn’t guarantee harm, but follow-up is key.

Q: Can I restart GLP-1 after giving birth?
A: Yes — but if you’re breastfeeding, you’ll need to pause until weaning. We help patients map this out so it feels seamless.

Q: Are compounded versions safer?
A: They still carry the same pregnancy precautions as branded drugs. Always treat them with equal caution.

Real Talk: Why This Matters

You deserve a weight loss journey that doesn’t punish you for being ready to build a family.

We won’t shame you for needing help to get here.
We won’t drop you when it’s time to shift focus.
And we won’t leave you guessing about what’s safe — or what comes next.

This is real clinical care. This is GOAL.MD.

Ready to Personalize Your Plan?

If you’re thinking about pregnancy but don’t want to lose everything you’ve gained…

We’ve got you.

💡 Book a free assessment today — and let’s build your transition plan together.
Your body. Your goals. Your future.

This is GOAL.MD — and we’re with you every step of the way.